Polyhexamethylene biguanide hydrochloride (English abbreviation PHMB) is a new generation of guanidine disinfectant, which has the advantages of broad-spectrum, long-lasting antibacterial, safe, non-toxic, and non-irritating. Polyhexamethylene biguanide hydrochloride (PHMB) has two forms, powder and aqueous solution, usually 20% aqueous solution. Polyhexamethylene biguanide hydrochloride (PHMB) has the functions of disinfection, sterilization and antiseptic. It can kill a variety of bacteria including Gram-positive bacteria, Gram-negative bacteria, fungi and yeasts. microorganism. Therefore, polyhexamethylene biguanide hydrochloride (PHMB) is often added to high-end products such as women’s lotions, disinfectant wipes, contact lens care solutions, etc., and is widely used in daily necessities, medical care, wet wipes, textiles and other fields.
CAS No.: 32289-58-0 (United States), 27083-27-8 (Europe), 91403-50-8 (INCI)
Molecular formula: C10H23N5
Molecular weight: 213.32
polyhexamethylene biguanide specification
|
Content |
20.0% Min |
|
PH |
4-5 |
|
Absorbance |
1.2-1.6 |
The sterilization principle of polyhexamethylene biguanide hydrochloride (PHMB)
The guanidine group of polyhexamethylene biguanide hydrochloride (PHMB) has high activity, which can make the polymer positively charged, and it is easily adsorbed by various negatively charged bacteria and viruses, thereby inhibiting the bacteria and viruses. The ability to divide makes it lose the ability to reproduce. In addition, the film formed by polyhexamethylene biguanide hydrochloride (PHMB) blocked the respiratory passages of microorganisms, resulting in rapid suffocation of microorganisms.
How to use polyhexamethylene biguanide hydrochloride (PHMB)
Polyhexamethylene biguanide hydrochloride (PHMB) is easily soluble in water and can be used after being diluted with pure water or other additives. However, because polyhexamethylene biguanide hydrochloride (PHMB) is a cationic polymer, it is contraindicated Compatible with anionic polymers. In addition, because polyhexamethylene biguanide hydrochloride (PHMB) is a broad-spectrum bactericide, there are big differences in usage and dosage when used in different industries and fields. It is recommended that you consult our company’s professionals or fully demonstrate before use experiment.
Properties and advantages of polyhexamethylene biguanide hydrochloride (PHMB)
1. Broad-spectrum bactericide, polyhexamethylene biguanide hydrochloride (PHMB) can kill a variety of bacteria and microorganisms including Gram-positive bacteria, Gram-negative bacteria, fungi and yeasts.
2. Non-corrosive, non-flammable and non-explosive, safe to use; easily soluble in water, easy to use.
3. Long-lasting: Because polyhexamethylene biguanide hydrochloride (PHMB) is a stable polymer, it is not volatile and does not decompose, so it can be stored for a long time, and polyhexamethylene biguanide hydrochloride (PHMB) ) After the solution is dried, a thin polymer layer of disinfectant can be formed on the surface of the object, which can keep the object in a good state after sterilization and prevent secondary pollution of the object. Under normal circumstances, various surfaces treated with an aqueous solution of polyhexamethylene biguanide hydrochloride (PHMB) will remain sterile for up to three months.
4. Polyhexamethylene biguanide hydrochloride (PHMB) is non-toxic to humans and animals at the concentration used. Because polyhexamethylene biguanide hydrochloride (PHMB) is a high-molecular polymer, it is not easily absorbed by animal tissues, which greatly reduces the toxicity of polyhexamethylene biguanide hydrochloride (PHMB), making it resistant to higher organisms. The cells are basically unaffected and belong to the actual non-toxic level. In addition, experiments have proved that polyhexamethylene biguanide hydrochloride (PHMB) can be degraded naturally and will not pollute the environment.
5. Polyhexamethylene biguanide hydrochloride (PHMB) is basically non-irritating to the skin at the concentration used.
Application of polyhexamethylene biguanide hydrochloride (PHMB)
medical hygiene
Polyhexamethylene biguanide hydrochloride (PHMB) can be used as a hand disinfectant after being compounded with alcohols and quaternary ammonium salt disinfectants. It is mainly used for disinfection in hospitals, high-end hotels and other places with high product requirements. Polyhexamethylene biguanide hydrochloride (PHMB) can also be used in antibacterial gauze and antibacterial dressings. Gauze or dressings containing 0.2% polyhexamethylene biguanide hydrochloride (PHMB) antibacterial ingredients can be used for surgical wounds and wound dressings to prevent bacterial infection and reproduction. Polyhexamethylene biguanide hydrochloride (PHMB) can repair damaged skin cells and accelerate metabolism.
Swimming pool disinfection
Polyhexamethylene biguanide hydrochloride (PHMB) for swimming pool disinfection is non-irritating, and the dosage is 10-50 ppm.
Daily care products
Polyhexamethylene biguanide hydrochloride (PHMB) can be used for disposable wet tissues, wet towels, napkins, especially for contact lens care solutions. Its non-toxic and non-irritating advantages have been widely recognized.
aquaculture
Adding polyhexamethylene biguanide hydrochloride (PHMB) to the aquatic water system can inhibit bacteria in the water system and prevent aquatic diseases caused by bacteria, such as red legs, rotted eyes, and ulcers. At the same time, it can also enhance water activity, reduce ammonia and phosphate in the water, control the growth of algae, naturally balance the ecosystem of the breeding pond, and play a good role in disease prevention and treatment.
textile
Polyhexamethylene biguanide hydrochloride (PHMB) can be used for antibacterial finishing of textiles. Due to its good thermal stability, it can be added to the melt spinning solution to make antibacterial synthetic fibers.
6. Polyhexamethylene biguanide hydrochloride (PHMB) is registered in the EU BPR and the US FDA.
